How CF affects the lungs

Cystic fibrosis (CF) is a genetic disease that causes a buildup of mucus in the lungs. This can lead to infections and a decline in lung function.6

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How CF affects the lungs

How CF affects the lungs

In people with CF, the CFTR protein does not work properly. This disrupts the balance of water and salt and reduces the amount of the airway surface liquid. As a result, the normally thin, slippery mucus becomes thick and sticky.4

How CF affects the lungs

How CF affects the lungs

The mucus eventually becomes so thick that the cilia cannot push it out of the lungs.4

How CF affects the lungs

How CF affects the lungs

As the mucus clogs the airways, it traps bacteria entering the lungs.6

How CF affects the lungs

How CF affects the lungs

The buildup of mucus makes it easier for bacteria to grow.6 This may lead to lung infections, which can cause more mucus to form.4

How CF affects the lungs

What is CAYSTON?

CAYSTON is a prescription inhaled antibiotic used to improve breathing symptoms in people with cystic fibrosis (CF) who have a lung infection due to Pseudomonas aeruginosa (Pa). CAYSTON is not a treatment for infections caused by other bacteria or viruses, such as the common cold. CAYSTON is used only with the Altera® Nebulizer System. It is not known if CAYSTON is safe and effective in children under the age of 7 or in patients with FEV1 <25% or >75% predicted.